Structure-activity relationships (SAR) analysis forms the bedrock in drug discovery. By systematically modifying the chemical structure of a lead compound and observing the resulting biological activity, researchers identify the key structural features responsible for desired effects. This insight guides further design of novel therapeutic agents w… Read More

Structure-activity relationships (SAR) analysis is crucial in drug discovery. By carefully tweaking the chemical structure of a lead compound and quantifying the resulting biological activity, researchers can elucidate the key structural features responsible for potency. This insight directs further optimization of novel therapeutic agents with imp… Read More

The control of chronic pain often involves a multi-faceted approach, incorporating pharmacological interventions designed to modulate various physiological pathways involved in pain perception and transmission. Commonly employed drug classes include nonsteroidal anti-inflammatory drugs (NSAIDs), which exert their analgesic effects by inhibiting cyc… Read More