Structure-activity relationships (SAR) analysis forms the bedrock in drug discovery. By systematically modifying the chemical structure of a lead compound and observing the resulting biological activity, researchers identify the key structural features responsible for desired effects. This insight guides further design of novel therapeutic agent… Read More

Structure-activity relationships (SAR) analysis is crucial in drug discovery. By carefully tweaking the chemical structure of a lead compound and quantifying the resulting biological activity, researchers can elucidate the key structural features responsible for potency. This insight directs further optimization of novel therapeutic agents with … Read More

The control of chronic pain often involves a multi-faceted approach, incorporating pharmacological interventions designed to modulate various physiological pathways involved in pain perception and transmission. Commonly employed drug classes include nonsteroidal anti-inflammatory drugs (NSAIDs), which exert their analgesic effects by inhibiting … Read More